Research projects

Selected
research

Experimental and computational projects in vascular biology, histomorphometry, gene regulation and cell biology.

2024–2025 · Histomorphometry · Vascular Biology

Aging-induced remodelling of pulmonary and cardiac arteries

Context

Graduate research at Lomonosov Moscow State University examining age-associated structural changes in human pulmonary and cardiac arteries.

Work

  • Quantitatively and qualitatively analysed more than 100 histology slides.
  • Developed an AI-assisted workflow to support histological quantification.
  • Synthesised findings from more than 200 scientific sources.
  • Presented results to a multidisciplinary committee.

Methods

Digital histomorphometry, image analysis, QuPath, tissue segmentation, quantitative morphology and literature synthesis.

2020–2022 · Genetics · Disease Modelling

Coffin-Siris syndrome in Drosophila melanogaster

Context

Research at the Laboratory of Gene Expression Regulation in Development, Institute of Gene Biology, Russian Academy of Sciences.

Work

  • Investigated intellectual disability in Coffin-Siris syndrome using Drosophila melanogaster.
  • Introduced a new DNA-extraction protocol, reducing turnaround time by 20% and increasing yield by 30%.
  • Automated downstream data analysis with Python.
  • Presented results at an international conference.

Methods

Molecular genetics, DNA extraction, PCR-based workflows, disease modelling and Python-assisted data analysis.

2019–2020 · Cell Biology · Cardiometabolic Research

T-cadherin and vascular protection

Context

Student research at the Laboratory of Gene and Cell Technologies, Faculty of Medicine, Lomonosov Moscow State University.

Work

  • Studied cardiometabolic relevance of T-cadherin and its protective effects against atherosclerosis and neointima proliferation.
  • Validated candidate T-cadherin-interacting proteins using Western blotting.
  • Built foundational expertise in cell culture, protein analysis and microscopy.

Methods

Western blotting, confocal microscopy, mammalian cell culture and protein interaction analysis.

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